Centre for Immunity, Infection and Evolution seminar: Etienne Pays (Laboratory of Molecular Parasitology, Université Libre de Bruxelles , Belgium)
- When: Friday 24 May 2013
- When: 4 - 5 pm
- Location: Lecture theatre 3, Ashworth Labs, Kings Buildings
- Title: Molecular dialogue between African trypanosomes and man
This seminar forms part of the Edinburgh Kinetoplastid Group Meeting - ALL WELCOME
Professor Pays’ seminar will be a review on what is known about the mutual adaptations between African trypanosomes and humans. He will summarize the current knowledge about human innate immunity against T. b. brucei, the mechanisms of resistance of T. b. rhodesiense and T. b. gambiense to this immunity, and the adaptations having allowed some humans to resist T. b. rhodesiense. Prof Pays will also talk about his group’s recent findings on the mechanisms of T. gambiense resistance to human serum.
For more information please visit Professor Pays’ website:
Some recent publications
- Adenylate cyclases of Trypanosoma brucei inhibit the innate immune response of the host. Salmon D, Vanwalleghem G, Morias Y, Denoeud J, Krumbholz C, Lhommé F, Bachmaier S, Kador M, Gossmann J, Dias FB, De Muylder G, Uzureau P, Magez S, Moser M, De Baetselier P, Van Den Abbeele J, Beschin A, Boshart M, Pays E. Science. 2012
- Association of trypanolytic ApoL1 variants with kidney disease in African Americans. Genovese G, Friedman DJ, Ross MD, Lecordier L, Uzureau P, Freedman BI, Bowden DW, Langefeld CD, Oleksyk TK, Uscinski Knob AL, Bernhard AJ, Hicks PJ, Nelson GW, Vanhollebeke B, Winkler CA, Kopp JB, Pays E, Pollak MR. Science. 2010
innate immunity against
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